Superbugs are bacterias that have gained resistance to multiple antibiotics used to treat the infections. Although antibiotic resistance is an evolutionary process, we can see this process speeding due to the misuse of antibiotics by doctors and patients. As it was stated by the CDC, more than 35,000 deaths per year are caused by antibiotic-resistant infections. Clostridioides difficile, Acinetobacter, Candi uris, Enterobacteriaceae, Neisseria gonorrhoeae are one of the highest risk germs that have gained antibiotic resistance. There is no clear distinction between the infection of a superbug and one that is not. It can only be seen once the patient’s symptoms get worse.
Research advances and there may be a finding that would allow us to fight antibiotic resistance. As it was mentioned in the article published in Science News, there is a new enzyme that helps the formation of the bacterial cell wall that could potentially be targeted by new antibiotics. Though there are five natural products that have inhibitory activities against MraY, on the molecular level it is very unclear. After more research, specific binding sites were found where nucleoside inhibitor binds on MraY’s surfaces. These binding sites could serve as targets for inhibitor-like antibiotics.
After analyzing both of these articles, I have come to realize that more precautions should be taken by patients and doctors when it comes to the usage of antibiotics. It is irritating to know that the ignorance of people is causing us to lose these abilities to fight off certain infections. I am glad that more research is being conducted to mend the problems that have been created. I am confident that we are going to be able to find a solution to antibiotic resistance. I, however, do believe is going to take more time and cost more lives.
